Search results for "pigment epithelial-cellls"

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Do nutritional supplements have a role in age macular degeneration prevention?

2013

Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (ω-3) supplements in AMD prevention.Materials and Methods. Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX andω-3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain).Results. High dietary intakes ofω-3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD. The Age-Related Eye Disease study (AREDS) showed a benefic…

medicine.medical_specialtyLuteineicosapentaenoic acidgenetic structuresmedicine.medical_treatmentSuplements nutritiusPhysiologypigment epithelial-celllsReview ArticleLower riskAntioxidantsclinical-trialchemistry.chemical_compoundlcsh:Ophthalmologybeta-CaroteneOPHTHALMOLOGYOmega-3 fatty acidsMedicineoxidative stressbusiness.industryVitamin Evitamin-EPreventionblue mountains eyeMacular degenerationMicronutrientmedicine.diseaseDietary supplementsEicosapentaenoic acidbeaver dam eyeAge macular degeneration (AMD)Retinal diseaseseye diseasesSurgeryZeaxanthinOphthalmologybeta-caroteneMalalties de la retinachemistrylcsh:RE1-994fatty-acid compositionsense organsbusinessgrowth-factor VEGFJournal of ophthalmology
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